AI Research Biostatistics Process Provenance

Steve Grambow

Associate Professor · AI Researcher · Speaker

I work on how academic and clinical research teams adopt AI into their workflows — the training programs, validation strategies, and governance structures that make integration responsible. My practice is grounded in Process Provenance: the principle that AI output is only defensible when the orchestration behind it is transparent and documented.

Steve Grambow

Research Focus

Deep research briefs generated by Rook (AI research engine) and curated for public release. Full archive in the vault.

Biostatistics

AI in Clinical Research

How AI systems are reshaping trial design, endpoint selection, and statistical reporting — and what rigor looks like in that context.

Integrity

Scientific Integrity & LLMs

Fabrication risk, citation hallucination, and what it takes for AI-assisted research to meet publication standards.

Practice

Responsible AI for Academics

Practical frameworks for using AI tools in academic workflows without compromising intellectual ownership or institutional policy.


Selected Publications

Peer-reviewed research on AI integration, responsible use, and clinical translation.

Biostatistics · LLM Workflows

Integrating large language models in biostatistical workflows for clinical and translational research

Grambow SC, Desai M, Weinfurt KP, Lindsell CJ, Pencina MJ, Rende L, & Pomann GM · Journal of Clinical and Translational Science, 9(1):e131, 2025

Cross-sectional survey of 69 biostatisticians across two academic medical centers. Of the 64% who reported using LLMs, nearly half used them daily — yet 70.7% reported significant errors including incorrect code, statistical misinterpretations, and hallucinated functions. Proposes eight guiding principles for responsible integration with emphasis on verification strategies and structured training.


Talks & Presentations

AI talks for academic, clinical, and professional audiences. Available for conferences, workshops, and institutional training.

2026

March 31, 2026 · Duke Department of Population Health Sciences · 15+ participants

From Compass to Practice: Building Your AI Workflow

March 25, 2026 · Duke DCRI Biostatistics AI Working Group · 15+ participants

Trust, but Verify: AI in Biomedical Research

Where the downstream consequence is a patient, not a product.

February 25, 2026 · Duke Department of Population Health Sciences · 30+ participants

The Practitioner's Compass: Responsible AI in Biomedical Research

Companion site →

February 12, 2026 · BIOTRAIN 754 "The Responsible Scientist II" · 80+ PhD SOM Students

The Steward's Schema: Responsible AI in Biomedical Research

Companion site →

January 30, 2026 · Second Annual Duke Department of Medicine AI & Medicine Symposium · 70+ participants

The Horizon Mandate: Orchestrating Professional Reliability in the AI Era

Companion site →

January 6, 2026 · North Carolina Alliance for Health Professions · 15+ participants

Architecting the Future of Health Work: AI Stewardship, Access, and Opportunity

GitHub repository →
2025

October 30, 2025 · LinkedIn Live Webinar · 30+ participants

When Trials Aren't Enough: How Real-World Data is Transforming Product Development & Market Access

With Hayden B. Bosworth

October 8, 2025 · Second Annual Duke Summit on AI for Health Innovation · 150+ participants

Beyond the Chatbot: Designing the Human Systems for AI-Powered Health Innovation

Companion site →

July 31, 2025 · Duke Learning Health System Training Program · 10 participants

Responsible AI Use in Biomedical Research: Balancing Innovation, Integrity, and Ethics

July 29, 2025 · Duke Community Affairs, Future Schools Workshop · 15 Durham Public Schools teachers & students

AI and LLMs Interactive Activities Workshop

July 14, 2025 · InnovateHER at Duke, Duke Community Affairs · 15 middle-school students

AI and LLMs Interactive Activities Workshop

July 11, 2025 · Duke & NCCU Summer Undergraduate Program · 25 participants

Responsible AI Use in Biomedical Research: Balancing Innovation, Integrity, and Ethics in the AI Era

April 16, 2025 · Duke CTSI Accelerator Core · 8 participants

AI at Work: Working Smarter with Large Language Models in Research, Writing, and Operations

February 13, 2025 · Duke OBGE Responsible Conduct of Research Course · ~100 students

Responsible Integration of AI Across the Biomedical Research Lifecycle

January 2025 · Duke Special Events Planners Council · 65 participants

Think Smarter Not Harder: How to Use AI to Help with Event Planning

With D. Stein and H. Koslow


Portfolio Sites

Provenance Labs is the hub. Each of these companion sites was built for a specific talk — the body of work it ties together.

Duke Summit on AI for Health Innovation · Oct 2025 · 150+ participants

The Bootstrapper's Playbook

Beyond the Chatbot: Designing the Human Systems for AI-Powered Health Innovation.

bootstrappers-playbook.netlify.app →

Duke AI & Medicine Symposium · Jan 2026 · 70+ participants

The Horizon Mandate

Orchestrating Professional Reliability in the AI Era.

horizon-mandate.netlify.app →

BIOTRAIN 754 "The Responsible Scientist II" · Feb 2026 · 80+ PhD students

The Steward's Schema

Responsible AI in Biomedical Research.

stewards-schema.netlify.app →

Duke Dept of Population Health Sciences · Feb 2026 · 30+ participants

The Practitioner's Compass

Responsible AI in Biomedical Research: from policy to workflow.

practitioners-compass.netlify.app →

Contact & Booking

Available for talks, workshops, consulting engagements, and media appearances on AI in academic and clinical contexts.

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